2/8/2024 0 Comments Pinpoint pharma reviews![]() ![]() Flecainide may cause or exacerbate arrhythmias in 1% of patients with preexisting paroxysmal supraventricular tachycardia and in 7% of patients with paroxysmal atrial fibrillation. CardiovascularĬardiovascular side effects including arrhythmias are the most serious side effects. Side effects are more likely when plasma flecainide concentrations are greater than 1.0 mcg/mL. Use of flecainide in this context is potentially harmful. The risk of death relative to placebo in patients with a recent history of Q-wave MI and non-Q-wave MI is 8.7 and 1.7, respectively. The Cardiac Arrhythmia Suppression Trial (CAST) revealed significantly higher mortality associated with flecainide in patients with a recent history (more than six days but less than two years prior to study) of myocardial infarction (MI) and non-life-threatening ventricular ectopy relative to placebo (5.1% versus 2.3%). loss in sexual ability, desire, drive, or performanceĪpplies to flecainide: oral tablet.increased sensitivity of the eyes to sunlight.excess air or gas in the stomach or intestines.decreased interest in sexual intercourse.feeling of constant movement of self or surroundings.continuing ringing or buzzing or other unexplained noise in the ears. ![]() Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.Ĭheck with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them: More common These side effects may go away during treatment as your body adjusts to the medicine. Some side effects of flecainide may occur that usually do not need medical attention. sores, ulcers, or white spots on the lips or in the mouth.general feeling of discomfort or illness.dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position.difficulty in passing urine (dribbling).unsteadiness, trembling, or other problems with muscle control or coordination.trembling or shaking of the hands or feet.shakiness in the legs, arms, hands, or feet.redness of the face, neck, arms, and occasionally, upper chest.Burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings.fast, irregular, pounding, or racing heartbeat or pulse.dizziness, fainting, or lightheadedness.Although not all of these side effects may occur, if they do occur they may need medical attention.Ĭheck with your doctor immediately if any of the following side effects occur while taking flecainide: More common Serious side effects of FlecainideĪlong with its needed effects, flecainide may cause some unwanted effects. Case reports of ventricular proarrhythmic effects in patients treated with flecainide for atrial fibrillation/flutter have included increased premature ventricular contractions, ventricular tachycardia, ventricular fibrillation, and death. Flecainide is not recommended for use in patients with chronic atrial fibrillation. Consider the risks of Class IC agents (including flecainide) and the lack of evidence of improved survival, which is generally unacceptable in a patient without life-threatening ventricular arrhythmias, even if the patient is experiencing unpleasant, but not life-threatening, symptoms or signs. Excessive mortality or nonfatal cardiac arrest rate was seen in patients with asymptomatic non-life-threatening ventricular arrhythmias and with myocardial infarction for more than six days but less than two years previously who received flecainide, compared with patients assigned to a carefully matched placebo in the Cardiac Arrhythmia Suppression Trial (CAST).
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